Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1949895 | 0.87 | GRB2 (0.44) | GRB2PTPN1GRIA1GRIA3GRIA2 | |
| SCHEMBL287394 | 0.82 | SLC7A5 (0.50) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| SCHEMBL287393 | 0.82 | SLC7A5 (0.50) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| SCHEMBL5875624 | 0.82 | SLC7A5 (0.50) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| SCHEMBL7818683 | 0.82 | GRB2 (0.45) | GRB2PTPN1GRIA1GRIA3GRIA2 | |
| SCHEMBL7818681 | 0.82 | GRB2 (0.45) | GRB2PTPN1GRIA1GRIA3GRIA2 | |
| SCHEMBL10608422 | 0.81 | SLC7A5 (0.50) | MAPTMEN1ALDH1A1CYP2C9KMT2A | |
| SCHEMBL296690 | 0.81 | SLC7A5 (0.50) | MAPTMEN1ALDH1A1CYP2C9KMT2A | |
| SCHEMBL38374 | 0.81 | SLC7A5 (0.50) | MAPTMEN1ALDH1A1CYP2C9KMT2A | |
| SCHEMBL17340412 | 0.81 | GRIA1 (0.49) | GRIA1GRIA3GRIA2GRIA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3061753-A1 | ENANTIO-SELECTIVE SYNTHESIS OF NON-NATURAL AMINO ACIDS | Universita' Degli Studi "G. d'Annunzio" Chieti-Pescara (IT) | 2016-08-31 | — | — | EP | disclosed |