⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78214 | 1.00 | — | — | |
| SCHEMBL1678165 | 0.94 | DNM1 (0.45) | — | |
| SCHEMBL1678302 | 0.91 | LCK (0.44) | — | |
| SCHEMBL6433035 | 0.88 | LCK (0.48) | — | |
| SCHEMBL79484 | 0.88 | LCK (0.48) | — | |
| SCHEMBL1879989 | 0.88 | LCK (0.48) | — | |
| SCHEMBL9177399 | 0.88 | LCK (0.48) | — | |
| SCHEMBL11337707 | 0.88 | LCK (0.48) | — | |
| SCHEMBL6435205 | 0.88 | LCK (0.48) | — | |
| SCHEMBL76976 | 0.88 | LCK (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077929-A1 | 2,3,5-SUBSTITUTED BIPHENYLS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999061410-A1 | 2,3,5-SUBSTITUTED BIPHENYLS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-02 | — | — | WO | disclosed |