Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 9/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820776 | 0.96 | MCHR1 (0.45) | MCHR1EPHX2LTA4HHRH3KCNH2 | |
| SCHEMBL7808978 | 0.88 | LTA4H (0.45) | LTA4HHRH3KCNH2TNF | |
| SCHEMBL7824372 | 0.87 | EPHX2 (0.44) | MCHR1EPHX2LTA4HHRH3KCNH2 | |
| SCHEMBL7821924 | 0.86 | EPHX2 (0.44) | MCHR1EPHX2LTA4HHRH3KCNH2 | |
| SCHEMBL7825781 | 0.85 | EPHX2 (0.44) | MCHR1EPHX2LTA4HHRH3KCNH2 | |
| SCHEMBL7820678 | 0.85 | LTA4H (0.47) | MCHR1EPHX2LTA4HHRH3ESR1 | |
| SCHEMBL7823241 | 0.84 | EPHX2 (0.44) | MCHR1EPHX2LTA4HHRH3KCNH2 | |
| Oxalic Acid SCHEMBL6172019 | 0.81 | F2 (0.49) | ESR1ESR2 | |
| SCHEMBL7830023 | 0.81 | LTA4H (0.46) | MCHR1POLBEPHX2LTA4HHRH3 | |
| SCHEMBL7819888 | 0.78 | MCHR1 (0.49) | MCHR1EPHX2LTA4HHRH3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1027051-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |