Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819902 | 0.88 | MCHR1 (0.46) | LTA4HHRH3KCNH2TNF | |
| SCHEMBL7820776 | 0.84 | MCHR1 (0.45) | LTA4HHRH3KCNH2PSMB1PSMB5 | |
| SCHEMBL7821101 | 0.83 | LTA4H (0.45) | LTA4HHRH3KCNH2PSMB1PSMB5 | |
| SCHEMBL7442242 | 0.79 | LTA4H (0.69) | LTA4HHRH3KCNH2PSMB1PSMB5 | |
| SCHEMBL7348199 | 0.77 | ESR1 (0.65) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7818364 | 0.77 | CD274 (0.43) | LTA4HHRH3KCNH2TNFPSMB1 | |
| SCHEMBL6965066 | 0.76 | LTA4H (0.54) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL6966960 | 0.76 | HRH3 (0.62) | LTA4HHRH3KCNH2PSMB1PSMB5 | |
| SCHEMBL7824372 | 0.76 | EPHX2 (0.44) | LTA4HHRH3KCNH2PSMB1PSMB5 | |
| SCHEMBL6968916 | 0.76 | LTA4H (0.53) | LTA4HHRH3KCNH2PSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1027051-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |