Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819938 | 0.88 | F2 (0.37) | S1PR1HRH3ACHEMAOB | |
| SCHEMBL7818365 | 0.81 | S1PR1 (0.45) | S1PR1S1PR5MCHR1HRH3CA12 | |
| SCHEMBL7819916 | 0.80 | S1PR1 (0.40) | S1PR1S1PR5MCHR1HRH3MEN1 | |
| SCHEMBL7818700 | 0.79 | MEN1 (0.41) | HRH3MEN1KMT2A | |
| SCHEMBL7818684 | 0.79 | DRD2 (0.41) | S1PR1S1PR5MCHR1HRH3 | |
| SCHEMBL7819929 | 0.79 | S1PR1 (0.38) | S1PR1S1PR5MCHR1HRH3MEN1 | |
| SCHEMBL7818112 | 0.78 | S1PR1 (0.47) | S1PR1S1PR5MCHR1HRH3MEN1 | |
| SCHEMBL6172541 | 0.77 | F2 (0.57) | S1PR1S1PR5MCHR1 | |
| SCHEMBL7830154 | 0.77 | IRAK4 (0.35) | MEN1KMT2A | |
| SCHEMBL6966701 | 0.74 | LTA4H (0.47) | MCHR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1027051-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |