Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPEPPS | P55786 | 2/20 | 0.38 |
| ▸ | PDE9A | O76083 | 5/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820731 | 0.89 | PDE9A (0.37) | NPEPPSPDE9APDE1CCAMK2DCCR6 | |
| SCHEMBL7822940 | 0.84 | CAMK2D (0.38) | NPEPPSPDE9APDE1CCAMK2DCCR6 | |
| SCHEMBL7822859 | 0.82 | PDE9A (0.34) | NPEPPSPDE9APDE1CCAMK2D | |
| SCHEMBL7823992 | 0.81 | PDE9A (0.35) | NPEPPSPDE9APDE1CCAMK2D | |
| SCHEMBL7812676 | 0.81 | PDE9A (0.36) | NPEPPSPDE9APDE1CCAMK2DCCR6 | |
| SCHEMBL7825914 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL7840389 | 0.80 | — | — | |
| SCHEMBL7827359 | 0.79 | CAMK2D (0.40) | NPEPPSPDE9APDE1CCAMK2DCCR6 | |
| SCHEMBL7823267 | 0.79 | MEN1 (0.34) | NPEPPSPDE9APDE1C | |
| Trifluoroacetic Acid SCHEMBL7822064 | 0.78 | HDAC3 (0.35) | PDE9APDE1CCAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | claimed |