Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.36 |
| ▸ | PDE9A | O76083 | 5/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820462 | 0.92 | CAMK2D (0.34) | CAMK2DNPEPPSPDE9APDE1C | |
| SCHEMBL7812544 | 0.90 | NPEPPS (0.38) | CAMK2DNPEPPSPDE9APDE1CKDM4E | |
| Trifluoroacetic Acid SCHEMBL7822064 | 0.90 | HDAC3 (0.35) | CAMK2DPDE9APDE1CMAPTKMT2A | |
| SCHEMBL7827359 | 0.90 | CAMK2D (0.40) | CAMK2DNPEPPSPDE9APDE1CCCR6 | |
| SCHEMBL7812676 | 0.90 | PDE9A (0.36) | CAMK2DNPEPPSPDE9APDE1CCCR6 | |
| SCHEMBL7823992 | 0.88 | PDE9A (0.35) | CAMK2DNPEPPSPDE9APDE1CKDM4E | |
| SCHEMBL7819430 | 0.85 | ALDH1A1 (0.36) | CAMK2DNPEPPSPDE9APDE1CKDM4E | |
| SCHEMBL7819975 | 0.84 | NPEPPS (0.38) | CAMK2DNPEPPSPDE9APDE1CCCR6 | |
| SCHEMBL7820731 | 0.84 | PDE9A (0.37) | CAMK2DNPEPPSPDE9APDE1CCCR6 | |
| SCHEMBL7819804 | 0.83 | PDE9A (0.34) | CAMK2DNPEPPSPDE9APDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | claimed |
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | disclosed |