Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384726 | 0.83 | MAPT (0.44) | KDM4ECYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL30299431 | 0.82 | KDM4E (0.55) | KDM4EPRNPRXFP1CYP1A2APEX1 | |
| SCHEMBL21450904 | 0.82 | RIPK2 (0.52) | CYP1A2APEX1RIPK2FFAR1KEAP1 | |
| SCHEMBL3071195 | 0.82 | KDM4E (0.55) | KDM4EPRNPRXFP1CYP1A2APEX1 | |
| SCHEMBL1851313 | 0.79 | PKM (0.49) | CYP1A2APEX1RIPK2FFAR1KEAP1 | |
| SCHEMBL20562926 | 0.79 | KEAP1 (0.49) | KDM4ECYP1A2APEX1RIPK2FFAR1 | |
| SCHEMBL27562903 | 0.78 | KDM4E (0.38) | KDM4ECYP1A2KMT2AMAPTHPGD | |
| SCHEMBL21811548 | 0.76 | CYP1A2 (0.42) | KDM4EPRNPRXFP1CYP1A2APEX1 | |
| SCHEMBL5506194 | 0.76 | LIG1 (0.47) | KDM4EPRNPRXFP1CYP1A2APEX1 | |
| SCHEMBL14235422 | 0.74 | APEX1 (0.69) | CYP1A2APEX1MEN1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332476-B2 | Fms-like tyrosine kinase inhibitors | 3SM BIOTRON INC. (TW) | 2022-05-17 | — | — | US | disclosed |
| US-20200131194-A1 | FMS-LIKE TYROSINE KINASE INHIBITORS | Sagabio Co., Ltd. (TW) | 2020-04-30 | — | — | US | disclosed |
| WO-2019191896-A1 | FMS-LIKE TYROSINE KINASE INHIBITORS | 3SM BIOTRON INC. (CN) | 2019-10-10 | — | — | WO | disclosed |
| EP-1131288-A1 | PYRROLIDINE DERIVATIVES-CCR-3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-09-12 | — | — | EP | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| US-6166015-A | Pyrrolidine derivatives-CCR-3 receptor antagonists | SYNTEX (U.S.A.) INC. (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000031032-A1 | PYRROLIDINE DERIVATIVES-CCR-3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-02 | — | — | WO | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332476-B2 | Fms-like tyrosine kinase inhibitors | FLT3, FLT4, FLT1 | KDM4E 1341/4885PRNP 4738/4885RXFP1 2088/4885 |
| US-20200131194-A1 | FMS-LIKE TYROSINE KINASE INHIBITORS | FLT3, FLT4, FLT1 | KDM4E 1341/4885PRNP 4738/4885RXFP1 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.