Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | HCN1 | O60741 | 1/20 | 0.33 |
| ▸ | HCN3 | Q9P1Z3 | 1/20 | 0.33 |
| ▸ | HCN2 | Q9UL51 | 1/20 | 0.33 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17606553 | 0.80 | EPHX1 (0.40) | OPRM1SMYD3GAACYP2C19 | |
| SCHEMBL2348782 | 0.80 | HCRTR2 (0.40) | SMYD3KMT2AKDM4EMEN1LMNA | |
| SCHEMBL1313231 | 0.80 | SMYD3 (0.44) | OPRM1SMYD3KMT2AKDM4EP2RX7 | |
| SCHEMBL28543808 | 0.78 | SMYD3 (0.43) | OPRM1SMYD3KMT2AKDM4EALOX15 | |
| SCHEMBL21551513 | 0.78 | SMYD3 (0.43) | OPRM1SMYD3KMT2AKDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL19995691 | 0.78 | SMYD3 (0.43) | OPRM1SMYD3KMT2AKDM4EP2RX7 | |
| SCHEMBL16365228 | 0.76 | TSHR (0.35) | SMYD3KMT2AKDM4ETSHR | |
| SCHEMBL21551515 | 0.76 | SMYD3 (0.44) | SMYD3KMT2AKDM4EMEN1LMNA | |
| SCHEMBL21551460 | 0.75 | SMYD3 (0.45) | OPRM1SMYD3KMT2AKDM4EP2RX7 | |
| SCHEMBL4113341 | 0.75 | OPRM1 (0.43) | OPRM1KMT2AKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323217-B2 | CARDIOVASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-11-27 | — | — | US | disclosed |
| US-20010034352-A1 | Piperidine-4 sulphonamide compounds | LES LABORATOIRES SERVIER (FR) | 2001-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034352-A1 | Piperidine-4 sulphonamide compounds | KDR, GLS, FLT1 | OPRM1 168/4885SMYD3 1509/4885KMT2A 2683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.