Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16893876 | 0.79 | PPARG (0.49) | PPARGPPARAPTPN7AGXTCYP1A2 | |
| SCHEMBL194634 | 0.78 | LMNA (0.42) | PPARGPPARAALDH1A1SLC6A4 | |
| SCHEMBL9064518 | 0.78 | CYP1A2 (0.48) | PPARGPPARAPTPN7AGXTCYP1A2 | |
| SCHEMBL28481701 | 0.77 | PPARG (0.49) | PPARGPPARAPTPN7KMT2ATDP1 | |
| SCHEMBL16893750 | 0.75 | PPARG (0.43) | PPARGPPARAPTPN7KMT2ATDP1 | |
| SCHEMBL11746367 | 0.75 | CYP1A2 (0.54) | PPARGPPARAPTPN7AGXTCYP1A2 | |
| SCHEMBL5481622 | 0.73 | PPARG (0.57) | PPARGPPARAPTPN7AGXTCYP1A2 | |
| SCHEMBL5479117 | 0.73 | PPARG (0.57) | PPARGPPARAPTPN7AGXTCYP1A2 | |
| SCHEMBL20911140 | 0.72 | CYP1A2 (0.50) | PPARGPPARAPTPN7CYP1A2CYP2A6 | |
| SCHEMBL21131538 | 0.72 | CYP1A2 (0.50) | PPARGPPARAPTPN7CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124804-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024719-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2000-05-04 | — | — | WO | disclosed |