Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.35 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.35 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3741031 | 0.92 | ACLY (0.39) | METAP2MEN1KMT2AKDM1ACYP3A4 | |
| SCHEMBL3745363 | 0.88 | ACLY (0.49) | METAP2ACLY | |
| SCHEMBL3899461 | 0.85 | MEN1 (0.44) | MEN1KMT2AALDH1A1WDR5KDM4E | |
| SCHEMBL3900098 | 0.84 | MEN1 (0.40) | METAP2MEN1KMT2AMCL1BCL2L1 | |
| SCHEMBL3749910 | 0.83 | ACLY (0.34) | METAP2ALDH1A1ACLY | |
| SCHEMBL3745614 | 0.83 | CCKBR (0.43) | MEN1KMT2AALDH1A1ACLYKDM4E | |
| SCHEMBL3747308 | 0.82 | ACLY (0.47) | METAP2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL1882959 | 0.82 | ACLY (0.37) | MEN1KMT2AKDM1ACYP2C9CYP2C19 | |
| SCHEMBL3911108 | 0.82 | ACLY (0.38) | METAP2MCL1ALDH1A1ACLYKDM4E | |
| SCHEMBL3746024 | 0.82 | ACLY (0.41) | MEN1KMT2AKDM1AALDH1A1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |