Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 20/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 20/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826302 | 0.88 | HIF1A (0.60) | HIF1AEPAS1EP300 | |
| SCHEMBL7825817 | 0.86 | HIF1A (0.49) | HIF1AEPAS1EP300 | |
| SCHEMBL7819712 | 0.86 | HIF1A (0.65) | HIF1AEPAS1EP300 | |
| SCHEMBL7823129 | 0.85 | HIF1A (0.51) | HIF1AEPAS1EP300 | |
| SCHEMBL7820055 | 0.84 | HIF1A (0.60) | HIF1AEPAS1EP300 | |
| SCHEMBL9201152 | 0.82 | HIF1A (0.53) | HIF1AEPAS1EP300 | |
| SCHEMBL7822894 | 0.79 | HIF1A (0.57) | HIF1AEPAS1EP300 | |
| SCHEMBL7821774 | 0.78 | HIF1A (0.48) | HIF1AEPAS1EP300 | |
| SCHEMBL7837529 | 0.76 | HIF1A (0.56) | HIF1AEPAS1EP300 | |
| SCHEMBL9196234 | 0.75 | HIF1A (0.50) | HIF1AEPAS1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1077888-C | Benzopyrans and pharmaceutical compositions containing them | NOVARTIS AG (CH) | 2002-01-16 | — | — | CN | disclosed |
| EP-0828733-B1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| US-5905156-A | POTASSIUM CHANNEL ACTIVATORS AND BRONCHODILATORS | NOVARTIS AG (CH) | 1999-05-18 | — | — | US | disclosed |