Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 20/20 | 0.56 |
| ▸ | EPAS1 | Q99814 | 20/20 | 0.56 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201152 | 0.85 | HIF1A (0.53) | HIF1AEPAS1EP300 | |
| SCHEMBL7812015 | 0.83 | HIF1A (0.69) | HIF1AEPAS1EP300 | |
| SCHEMBL9196234 | 0.80 | HIF1A (0.50) | HIF1AEPAS1EP300 | |
| SCHEMBL8006277 | 0.80 | HIF1A (0.53) | HIF1AEPAS1EP300 | |
| SCHEMBL8003071 | 0.79 | HIF1A (0.49) | HIF1AEPAS1EP300 | |
| SCHEMBL7835766 | 0.79 | HIF1A (0.49) | HIF1AEPAS1EP300 | |
| SCHEMBL7819712 | 0.76 | HIF1A (0.65) | HIF1AEPAS1EP300 | |
| SCHEMBL7820331 | 0.76 | HIF1A (0.48) | HIF1AEPAS1EP300 | |
| SCHEMBL9203941 | 0.75 | HIF1A (0.57) | HIF1AEPAS1EP300 | |
| SCHEMBL8813555 | 0.75 | HIF1A (0.49) | HIF1AEPAS1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747374-B1 | Sulfonamido substituted benzopyran potassium channel activators | BRISTOL MYERS SQUIBB CO (US) | 2001-12-12 | — | — | EP | disclosed |
| US-5869478-A | ADMINISTERING AS ANTIISCHEMIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0747374-A1 | Sulfonamido substituted benzopyran potassium channel activators | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |