Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356126 | 0.96 | ALDH1A1 (0.69) | ALDH1A1HPGDHSD17B10TDP1L3MBTL1 | |
| SCHEMBL2525145 | 0.89 | CA2 (0.62) | ALDH1A1HPGDHSD17B10TDP1L3MBTL1 | |
| SCHEMBL92022 | 0.89 | CA2 (0.62) | ALDH1A1HPGDHSD17B10TDP1L3MBTL1 | |
| SCHEMBL11423252 | 0.89 | ALDH1A1 (0.80) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL4444930 | 0.87 | CA2 (0.60) | ALDH1A1HPGDHSD17B10TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2529407 | 0.87 | CA2 (0.60) | ALDH1A1HPGDHSD17B10TDP1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL22042020 | 0.87 | CA2 (0.60) | ALDH1A1HPGDHSD17B10TDP1L3MBTL1 | |
| SCHEMBL11424079 | 0.87 | ALDH1A1 (0.77) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL11432001 | 0.87 | ALDH1A1 (0.77) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL388578 | 0.87 | CA2 (0.60) | ALDH1A1HPGDHSD17B10TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |