SCHEMBL7821068

SCHEMBL7821068

O=C=N[C@H](C(=O)O)C(OCc1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 3/20 0.43
KMT2A Q03164 3/20 0.43
SLC1A3 P43003 2/20 0.43
SLC1A2 P43004 2/20 0.43
CYP1A2 P05177 2/20 0.43
MEN1 O00255 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 1/20 0.36
ALDH1A1 P00352 3/20 0.36
SLC6A2 P23975 2/20 0.35
SLC6A3 Q01959 2/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
SLC6A4 P31645 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7819092 0.80 SLC1A3 (0.43) SLC1A1KMT2ASLC1A3SLC1A2CYP1A2
SCHEMBL2269233 0.77 SLC1A3 (0.49) SLC1A1KMT2ASLC1A3SLC1A2CYP1A2
SCHEMBL29277743 0.74 SLC6A2 (0.50) SLC1A1KMT2ASLC1A3SLC1A2CYP1A2
SCHEMBL29277741 0.74 SLC6A2 (0.50) SLC1A1KMT2ASLC1A3SLC1A2CYP1A2
SCHEMBL8508888 0.72 ALDH1A1 (0.50) SLC1A1KMT2ASLC1A3SLC1A2CYP1A2
SCHEMBL11094947 0.71 SLC1A3 (0.53) SLC1A1KMT2ASLC1A3SLC1A2CYP1A2
SCHEMBL27857348 0.71 SLC1A3 (0.53) SLC1A1KMT2ASLC1A3SLC1A2CYP1A2
SCHEMBL6963343 0.71 ALDH1A1 (0.49) KMT2AALDH1A1SLC6A2SLC6A3MAPK1
SCHEMBL12935748 0.71 ALDH1A1 (0.49) KMT2AALDH1A1SLC6A2SLC6A3MAPK1
SCHEMBL669496 0.70 CYP2D6 (0.41) CYP2D6SMN1; SMN2ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1078919-A1 SYNTHESIS OF $g(a)-AMINO-$g(a)',$g(a)'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF $g(b)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME KANEKA CORPORATION (JP) 2001-02-28 EP disclosed