SCHEMBL7819092

SCHEMBL7819092

O=C=N[C@H](C(=O)O)C(Cc1ccccc1)OCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 3/20 0.43
SLC1A2 P43004 3/20 0.43
SLC1A1 P43005 3/20 0.43
CYP1A2 P05177 2/20 0.43
MEN1 O00255 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP2D6 P10635 1/20 0.43
PPARG P37231 4/20 0.40
PPARA Q07869 4/20 0.40
SRR Q9GZT4 2/20 0.40
ALPI P09923 1/20 0.39
PKM P14618 1/20 0.39
PTGS1 P23219 1/20 0.39
XIAP P98170 1/20 0.39
SLC7A5 Q01650 1/20 0.39
CPA1 P15085 5/20 0.37
CPA3 P15088 2/20 0.37
FOLH1 Q04609 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7821232 0.81 CYP1A2 (0.39) CYP1A2MEN1CYP2C9CYP2C19KMT2A
SCHEMBL7808946 0.81 CYP1A2 (0.39) CYP1A2MEN1CYP2C9CYP2C19KMT2A
SCHEMBL7821068 0.80 SLC1A1 (0.43) SLC1A3SLC1A2SLC1A1CYP1A2MEN1
SCHEMBL7065597 0.78 SLC1A2 (0.38) SLC1A3SLC1A2SLC1A1CYP1A2MEN1
SCHEMBL27857348 0.77 SLC1A3 (0.53) SLC1A3SLC1A2SLC1A1CYP1A2MEN1
SCHEMBL11094947 0.77 SLC1A3 (0.53) SLC1A3SLC1A2SLC1A1CYP1A2MEN1
SCHEMBL2269233 0.77 SLC1A3 (0.49) SLC1A3SLC1A2SLC1A1CYP1A2MEN1
SCHEMBL4829905 0.75 SLC1A3 (0.40) SLC1A3SLC1A2SLC1A1CYP1A2MEN1
SCHEMBL7266856 0.72 ALDH1A1 (0.46) CYP1A2KMT2AMAPTTDP1L3MBTL1
SCHEMBL7266845 0.72 ALDH1A1 (0.46) CYP1A2KMT2AMAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1078919-A1 SYNTHESIS OF $g(a)-AMINO-$g(a)',$g(a)'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF $g(b)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME KANEKA CORPORATION (JP) 2001-02-28 EP disclosed