Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 3/20 | 0.46 |
| ▸ | S100A4 | P26447 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28773684 | 0.98 | ALDH1A1 (0.71) | ALDH1A1TDP1LMNAHTR7SCN2A | |
| SCHEMBL2958562 | 0.86 | ALDH1A1 (0.92) | ALDH1A1TDP1POLBMAPK1PTPN1 | |
| SCHEMBL30196067 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1PTPN1PTPRC | |
| Benzene SCHEMBL28038982 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1PTPN1PTPRC | |
| SCHEMBL28240316 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNAHTR7SCN2A | |
| SCHEMBL44392 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1PTPN1PTPRC | |
| SCHEMBL6747891 | 0.84 | ALDH1A1 (0.74) | ALDH1A1TDP1MAPK1MAOBPTPN1 | |
| SCHEMBL11792031 | 0.83 | ALDH1A1 (0.88) | ALDH1A1TDP1LMNAPOLBMAPK1 | |
| Water SCHEMBL1828402 | 0.83 | ALDH1A1 (0.96) | ALDH1A1TDP1MAPK1PTPN1PTPRC | |
| Methane SCHEMBL2186810 | 0.83 | ALDH1A1 (0.96) | ALDH1A1TDP1MAPK1PTPN1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780363-B1 | Bisazo-benzofuran compounds, their use as charge carrier generating compounds | SHARP KK (JP) | 2001-09-26 | — | — | EP | claimed |
| CN-101152185-B | Use of heterocyclic compounds as SCCE inhibitors | AREXIS AB | 2010-12-08 | — | — | CN | disclosed |
| CN-100518740-C | Pharmaceutical use of heterocyclic compounds as SCCE inhibitors | AREXIS AB (SE) | 2009-07-29 | — | — | CN | disclosed |
| CN-101152185-A | Use of heterocyclic compounds as scce inhibitors | AREXIS AB (SE) | 2008-04-02 | — | — | CN | disclosed |
| CN-1802160-A | Use of heterocyclic compounds as SCCE inhibitors | AREXIS AB (SE) | 2006-07-12 | — | — | CN | disclosed |
| EP-0780363-B1 | Bisazo-benzofuran compounds, their use as charge carrier generating compounds | SHARP KK (JP) | 2001-09-26 | — | — | EP | disclosed |
| EP-0780363-A1 | Bisazo-benzofuran compounds, their use as charge carrier generating compounds and intermediates for their preparation | SHARP KABUSHIKI KAISHA (JP) | 1997-06-25 | — | — | EP | disclosed |
| US-5138098-A | Catalytic actlation using complexing agent | AMOCO CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| US-4401603-A | CHLORINATION OF THE SOLUTION OR SUSPENSION FORMED BY THE FORMYLATION OF AN ARYLAMINE IN A SOLVENT | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |