Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6340423 | 0.80 | CYP1A2 (0.54) | CYP2C19MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7821178 | 0.74 | CYP1A2 (0.40) | CYP2C19MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL3625735 | 0.69 | ALDH1A1 (0.47) | POLBCYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL37688 | 0.69 | TSHR (0.39) | CYP2C19MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21400967 | 0.68 | CYP2D6 (0.33) | CYP2C19 | |
| SCHEMBL1349897 | 0.68 | ALDH1A1 (0.55) | POLBCYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL23175300 | 0.67 | CYP2D6 (0.38) | CYP2C19MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL1938911 | 0.67 | CYP2D6 (0.38) | CYP2C19MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21402676 | 0.67 | CYP2D6 (0.38) | CYP2C19MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL17911359 | 0.67 | CYP2D6 (0.38) | CYP2C19MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |