Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6340423 | 0.83 | CYP1A2 (0.54) | CYP1A2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4610015 | 0.75 | MAPT (0.54) | MEN1KMT2AMAPTTDP1BCHE | |
| SCHEMBL6754408 | 0.75 | MAPT (0.54) | MEN1KMT2AMAPTTDP1BCHE | |
| SCHEMBL4609127 | 0.75 | MAPT (0.54) | MEN1KMT2AMAPTTDP1BCHE | |
| SCHEMBL7821173 | 0.74 | POLB (0.43) | CYP1A2MEN1KMT2AMAPTTDP1 | |
| SCHEMBL9508850 | 0.74 | MAPT (0.46) | CYP1A2MEN1KMT2AMAPTTDP1 | |
| SCHEMBL6754133 | 0.73 | ALDH1A1 (0.51) | MEN1KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL6754130 | 0.73 | ALDH1A1 (0.51) | MEN1KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL9623550 | 0.72 | MEN1 (0.44) | CYP1A2MEN1KMT2AMAPTTDP1 | |
| SCHEMBL9623545 | 0.72 | MEN1 (0.44) | CYP1A2MEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |