SCHEMBL782147

SCHEMBL782147

C=CN1CCc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
ALDH1A1 P00352 5/20 0.50
MAPT P10636 5/20 0.50
GAA P10253 1/20 0.50
USP2 O75604 1/20 0.48
CDK4 P11802 1/20 0.48
ALOX15 P16050 1/20 0.48
CCND1 P24385 1/20 0.48
SIGMAR1 Q99720 2/20 0.46
NOTUM Q6P988 1/20 0.43
TSHR P16473 3/20 0.42
KDM4E B2RXH2 3/20 0.41
THRB P10828 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
TNNI3 P19429 1/20 0.40
HTT P42858 1/20 0.40
TNNT2 P45379 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL11307340 0.98 MEN1 (0.49) MEN1KMT2AALDH1A1MAPTGAA
SCHEMBL9217182 0.88 SMN1; SMN2 (0.49) MEN1KMT2AALDH1A1MAPTGAA
SCHEMBL25159595 0.80 HSD17B3 (0.47) MEN1KMT2AALDH1A1MAPTGAA
SCHEMBL2319502 0.79 MEN1 (0.50) MEN1KMT2AALDH1A1MAPTGAA
SCHEMBL11804991 0.79 MEN1 (0.50) MEN1KMT2AALDH1A1MAPTGAA
SCHEMBL223608 0.79 MEN1 (0.54) MEN1KMT2AALDH1A1MAPTGAA
SCHEMBL1198901 0.79 ALDH1A1 (0.50) MEN1KMT2AALDH1A1MAPTGAA
SCHEMBL2596389 0.76 MEN1 (0.51) MEN1KMT2AALDH1A1MAPTGAA
Naphthalene SCHEMBL11707755 0.73 ADRA1D (0.35) MEN1KMT2AALDH1A1MAPTGAA
SCHEMBL12288818 0.73 NOTUM (0.50) MEN1KMT2AALDH1A1CDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111434651-B Aromatic pyridazine compound, preparation method and application 天津大学 2023-08-22 CN disclosed
CN-115636812-A Terminal alkenyl indoline derivative and preparation method thereof 江汉大学 2023-01-24 CN disclosed
CN-113004803-A Polishing slurry composition capable of realizing multiple selection ratios 凯斯科技股份有限公司 2021-06-22 CN disclosed
CN-112930377-A Polishing slurry composition and method for preparing the same 凯斯科技股份有限公司 2021-06-08 CN disclosed
CN-111434651-A Aromatic pyridazine compound, preparation method and application 天津大学 2020-07-21 CN disclosed
US-10031394-B2 Electrophoretic particle, electrophoretic particle dispersion liquid, display medium, and display device E INK CORPORATION (US) 2018-07-24 US disclosed
US-9822201-B2 Reflective particle, particle dispersion liquid, display medium, and display device FUJIFILM CORPORATION (JP) 2017-11-21 US disclosed
WO-2017120429-A1 SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE CS Pharmasciences, Inc. (US) 2017-07-13 WO disclosed
US-9671667-B2 Electrophoretic particle, electrophoretic particle dispersion liquid, display medium, and display device E INK CORPORATION (US) 2017-06-06 US disclosed
US-20150353661-A1 REFLECTIVE PARTICLE, PARTICLE DISPERSION LIQUID, DISPLAY MEDIUM, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-10 US disclosed
US-20130222887-A1 ELECTROPHORETIC PARTICLE, ELECTROPHORETIC PARTICLE DISPERSION LIQUID, DISPLAY MEDIUM, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-20130222888-A1 ELECTROPHORETIC PARTICLE, ELECTROPHORETIC PARTICLE DISPERSION LIQUID, DISPLAY MEDIUM, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-20130222884-A1 ELECTROPHORETIC PARTICLE, PARTICLE DISPERSION LIQUID FOR DISPLAY, DISPLAY MEDIUM AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-20130222882-A1 POLYMER DISPERSANT FOR IMAGE DISPLAY PARTICLES, IMAGE DISPLAY PARTICLES, DISPERSION LIQUID FOR IMAGE DISPLAY PARTICLES, DISPLAY MEDIUM, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-8331015-B2 Display medium and display device FUJI XEROX CO., LTD. (JP) 2012-12-11 US disclosed
US-20120069423-A1 DISPLAY MEDIUM AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2012-03-22 US disclosed
US-20110175939-A1 DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2011-07-21 US disclosed
US-7796323-B2 Display particle and method for producing the same, display particle dispersion, display medium, and display device FUJI XEROX CO., LTD. (JP) 2010-09-14 US disclosed
US-20090269683-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND COLOR FILTERS JSR CORPORATION (JP) 2009-10-29 US disclosed
US-20090201569-A1 DISPLAY PARTICLE AND METHOD FOR PRODUCING THE SAME, DISPLAY PARTICLE DISPERSION, DISPLAY MEDIUM, AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2009-08-13 US disclosed