Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 7/20 | 1.00 |
| ▸ | NOS1 | P29475 | 6/20 | 1.00 |
| ▸ | NOS3 | P29474 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067374 | 0.88 | NOS2 (1.00) | NOS2NOS1NOS3ALDH1A1KDM4E | |
| SCHEMBL7822522 | 0.87 | NOS2 (1.00) | NOS2NOS1NOS3ALDH1A1KDM4E | |
| SCHEMBL17303758 | 0.86 | NOS2 (0.76) | NOS2NOS1NOS3ALDH1A1KDM4E | |
| SCHEMBL5879617 | 0.85 | NOS2 (1.00) | NOS2NOS1NOS3ALDH1A1KDM4E | |
| SCHEMBL15829843 | 0.85 | NOS2 (0.73) | NOS2NOS1NOS3ALDH1A1KDM4E | |
| SCHEMBL15834813 | 0.84 | NOS2 (0.73) | NOS2NOS1NOS3ALDH1A1KDM4E | |
| SCHEMBL17303813 | 0.82 | NOS2 (0.70) | NOS2NOS1NOS3ALDH1A1KDM4E | |
| SCHEMBL9108352 | 0.82 | NOS2 (0.70) | NOS2NOS1NOS3ALDH1A1KDM4E | |
| SCHEMBL17303996 | 0.81 | NOS2 (0.69) | NOS2NOS1NOS3ALDH1A1KDM4E | |
| SCHEMBL15829981 | 0.81 | NOS2 (0.69) | NOS2NOS1NOS3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| EP-1124821-A1 | COMPOUNDS | AstraZeneca AB (SE) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000027842-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2000-05-18 | — | — | WO | disclosed |