Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.51 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.51 |
| ▸ | THRA | P10827 | 8/20 | 0.49 |
| ▸ | THRB | P10828 | 8/20 | 0.49 |
| ▸ | RARB | P10826 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712415 | 0.86 | RARB (0.60) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9698325 | 0.86 | RARB (0.60) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL10626442 | 0.86 | RARB (0.60) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL10626429 | 0.86 | THRA (0.63) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL11071710 | 0.86 | THRA (0.63) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL6655352 | 0.86 | THRA (0.63) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9698319 | 0.86 | THRA (0.63) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL6886269 | 0.86 | THRA (0.63) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL6653441 | 0.86 | THRA (0.63) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL1790208 | 0.85 | TSHR (0.48) | THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |