SCHEMBL1790208

SCHEMBL1790208

CCCCCCc1ccccc1C(=O)OC(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
PPARA Q07869 3/20 0.47
BID P55957 3/20 0.47
MCL1 Q07820 3/20 0.47
BCL2L1 Q07817 2/20 0.47
BAK1 Q16611 2/20 0.47
KAT8 Q9H7Z6 2/20 0.47
PPARG P37231 2/20 0.47
EP300 Q09472 1/20 0.47
KAT2A Q92830 1/20 0.47
KAT2B Q92831 1/20 0.47
KAT5 Q92993 1/20 0.47
SAE1 Q9UBE0 1/20 0.47
LIPG Q9Y5X9 1/20 0.46
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
SLC16A3 O15427 1/20 0.45
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27934134 0.99 TSHR (0.46) TSHRALDH1A1LMNAPPARABID
SCHEMBL8512473 0.94 LMNA (0.46) TSHRALDH1A1LMNASLC16A3TP53
SCHEMBL30656414 0.91 TSHR (0.53) TSHRALDH1A1LMNAPPARABID
SCHEMBL28012546 0.88 LMNA (0.49) TSHRALDH1A1LMNAPPARAPPARG
SCHEMBL8512469 0.86 TSHR (0.51) TSHRALDH1A1LMNALIPGTHRA
SCHEMBL570967 0.86 BID (0.54) TSHRALDH1A1LMNAPPARABID
SCHEMBL9578113 0.85 TSHR (0.50) TSHRALDH1A1LMNAPPARABID
SCHEMBL7821680 0.85 PLK1 (0.51) ALDH1A1THRATHRB
SCHEMBL8435790 0.85 TSHR (0.54) TSHRALDH1A1LMNATHRATHRB
SCHEMBL28543543 0.84 BID (0.52) ALDH1A1PPARABIDMCL1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107847422-A Include the acrylic acid of palkoxy benzene base substitution(APP)The stable composition of the light of copolymer derivative 浩思特创新科技公司 2018-03-27 CN claimed
CN-107638307-A A kind of sunscreen spray composition 澳宝化妆品(惠州)有限公司 2018-01-30 CN claimed
CN-107530252-A Water-based cosmetic composition without surfactant 纳欧斯实验室 2018-01-02 CN claimed
US-11628134-B2 Cellulose acetate particles, cosmetic composition, and method of producing cellulose acetate particles DAICEL CORPORATION (JP) 2023-04-18 US disclosed
US-20230044107-A1 WATER IN OIL TYPE EMULSION COSMETIC SHISEIDO COMPANY, LTD. (JP) 2023-02-09 US disclosed
US-11160736-B2 Lip cosmetic SHISEIDO COMPANY, LTD. (JP) 2021-11-02 US disclosed
US-20210322296-A1 AQUEOUS DISPERSION COMPOSITION AND USE THEREOF DOW TORAY CO., LTD. (JP) 2021-10-21 US disclosed
US-20200222290-A1 WATER-IN-OIL-TYPE SOLID COSMETIC SHISEIDO COMPANY, LTD. (JP) 2020-07-16 US disclosed
US-20200179261-A1 CELLULOSE ACETATE PARTICLES, COSMETIC COMPOSITION, AND METHOD OF PRODUCING CELLULOSE ACETATE PARTICLES DAICEL CORPORATION (JP) 2020-06-11 US disclosed
CN-110496086-A A kind of cool sun-prevention air cushion of the Herba Dendrobii extract containing iron sheet and preparation method thereof Guangdong shengmei cosmetic co ltd 2019-11-26 CN disclosed
US-10449135-B2 Solublizing agents for UV filters in cosmetic formulations BASF SE (DE) 2019-10-22 US disclosed
US-8440172-B2 Stable soluble salts of phenylbenzimidazole sulfonic acid at PHS at or below 7.0 SYMRISE AG (DE) 2013-05-14 US disclosed
US-20130096208-A1 COSMETIC PREPARATION HAVING A CONTENT OF ACYL ARGINATES BEIERSDORF AG (DE) 2013-04-18 US disclosed
US-8263051-B2 Photostabilization of resveratrol with alkoxycrylene compounds HALLSTAR INNOVATIONS CORP. (US) 2012-09-11 US disclosed
US-20120128611-A1 UV FILTER COMBINATIONS COMPRISING BENZYLIDENE MALONATES BASF SE (DE) 2012-05-24 US disclosed
WO-2012052383-A2 POLYURETHANE THICKENER BASF SE (DE) 2012-04-26 WO disclosed
US-20120093744-A1 MODIFIED OILS AND MULTIPLE EMULSIONS GIULIANI SPA (IT) 2012-04-19 US disclosed
US-20110251242-A1 PHOTOSTABILIZATION OF RESVERATROL WITH ALKOXYCRYLENE COMPOUNDS HALLSTAR INNOVATIONS CORP. (US) 2011-10-13 US disclosed
US-20110123468-A1 USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS BASF SE (DE) 2011-05-26 US disclosed
US-20100183531-A1 STABLE SOLUBLE SALTS OF PHENYLBENZIMIDAZOLE SULFONIC ACID AT PHS AT OR BELOW 7.0 SYMRISE GMBH & CO. KG (DE) 2010-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210322296-A1 AQUEOUS DISPERSION COMPOSITION AND USE THEREOF CUTA, ADH1A, ADH1C TSHR 2977/4885ALDH1A1 803/4885LMNA 882/4885
US-20100183531-A1 STABLE SOLUBLE SALTS OF PHENYLBENZIMIDAZOLE SULFONIC ACID AT PHS AT OR BELOW 7.0 TYR, H1-5, PAH TSHR 3379/4885ALDH1A1 2231/4885LMNA 3887/4885
US-20120128611-A1 UV FILTER COMBINATIONS COMPRISING BENZYLIDENE MALONATES VDR, MSH6, SERPINB6 TSHR 166/4885ALDH1A1 531/4885LMNA 1960/4885
US-20110123468-A1 USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS CBR3, SCO2, CBR1 TSHR 1461/4885ALDH1A1 690/4885LMNA 2319/4885
US-20130096208-A1 COSMETIC PREPARATION HAVING A CONTENT OF ACYL ARGINATES ASS1, ARGLU1, ARG1 TSHR 2295/4885ALDH1A1 1001/4885LMNA 1816/4885
US-10449135-B2 Solublizing agents for UV filters in cosmetic formulations C1S, H1-0, H1-2 TSHR 1227/4885ALDH1A1 269/4885LMNA 1699/4885
US-20110251242-A1 PHOTOSTABILIZATION OF RESVERATROL WITH ALKOXYCRYLENE COMPOUNDS CBR1, CBR3, PC TSHR 4174/4885ALDH1A1 223/4885LMNA 636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.