Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19083027 | 0.81 | GAA (0.67) | GAAALDH1A1HTTLMNAKDM4E | |
| SCHEMBL6432060 | 0.74 | ALDH1A1 (0.60) | GAAALDH1A1HSD17B10HTTALOX15 | |
| SCHEMBL23493795 | 0.73 | GAA (0.57) | GAAALDH1A1HSD17B10HTTALOX15 | |
| SCHEMBL31307827 | 0.73 | GAA (0.57) | GAAALDH1A1HSD17B10HTTALOX15 | |
| SCHEMBL5338687 | 0.72 | MAPT (0.76) | ALDH1A1HTTHPGDLMNATP53 | |
| SCHEMBL5331381 | 0.72 | TP53 (0.74) | ALDH1A1HSD17B10HTTHPGDLMNA | |
| SCHEMBL14426478 | 0.72 | GAA (0.82) | GAAALDH1A1HTTHPGDTSHR | |
| SCHEMBL5335177 | 0.71 | L3MBTL1 (0.63) | ALDH1A1HSD17B10HTTHPGDLMNA | |
| SCHEMBL11887417 | 0.71 | KMT2A (0.80) | ALDH1A1HSD17B10HTTHPGDTSHR | |
| SCHEMBL13401419 | 0.70 | POLB (0.77) | GAAALDH1A1HSD17B10ALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |