Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825233 | 0.78 | ESR2 (0.64) | ESR2L3MBTL1HPGDKMT2AMAPT | |
| SCHEMBL39472 | 0.78 | HPGD (0.78) | ESR2L3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL9263396 | 0.77 | ESR2 (0.62) | ESR2L3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL28056476 | 0.76 | L3MBTL1 (0.81) | ESR2L3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL2463968 | 0.75 | ESR2 (0.59) | ESR2ALDH1A1MAPTTDP1HTT | |
| SCHEMBL1847303 | 0.74 | ESR2 (0.58) | ESR2L3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL9576479 | 0.72 | L3MBTL1 (0.60) | ESR2L3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL7508551 | 0.72 | ESR2 (0.56) | ESR2L3MBTL1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL8456613 | 0.72 | HPSE (0.58) | ESR2L3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL9127093 | 0.72 | L3MBTL1 (0.64) | ESR2L3MBTL1HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |