Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | PPOX | P50336 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31719692 | 0.87 | PARP14 (0.61) | ESR2L3MBTL1MAPTTDP1LMNA | |
| SCHEMBL10980033 | 0.82 | MAPT (0.61) | L3MBTL1MAPTTDP1LMNAKMT2A | |
| SCHEMBL7821791 | 0.78 | ESR2 (1.00) | ESR2L3MBTL1MAPTTDP1KMT2A | |
| SCHEMBL7508551 | 0.78 | ESR2 (0.56) | ESR2L3MBTL1TDP1LMNAKMT2A | |
| SCHEMBL5539772 | 0.75 | TTR (0.64) | MAPTTDP1LMNAKMT2APOLB | |
| SCHEMBL10786867 | 0.75 | TDP1 (0.81) | MAPTTDP1LMNAKMT2APOLB | |
| SCHEMBL31090831 | 0.74 | MAPT (0.60) | MAPTTDP1LMNAKMT2APOLB | |
| SCHEMBL10588184 | 0.74 | MAPT (0.60) | MAPTTDP1LMNAKMT2APOLB | |
| SCHEMBL10662277 | 0.74 | LMNA (0.61) | MAPTTDP1LMNAKMT2APOLB | |
| SCHEMBL31090851 | 0.74 | LMNA (0.62) | MAPTTDP1LMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |