Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MPL | P40238 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dobesilic Acid SCHEMBL370202 | 1.00 | LMNA (0.70) | LMNAHSD17B10HPGDHIF1APTGS1 | |
| Dobesilic Acid SCHEMBL232087 | 0.98 | LMNA (0.72) | LMNAHSD17B10HPGDHIF1APTGS1 | |
| Dobesilic Acid SCHEMBL29389625 | 0.98 | LMNA (0.72) | LMNAHSD17B10HPGDHIF1APTGS1 | |
| Dobesilic Acid SCHEMBL9790423 | 0.95 | LMNA (0.70) | LMNAHSD17B10HPGDHIF1APTGS1 | |
| Dobesilic Acid SCHEMBL10589964 | 0.95 | HSD17B10 (0.70) | LMNAHSD17B10HPGDHIF1APTGS1 | |
| Dobesilic Acid SCHEMBL344443 | 0.95 | LMNA (0.70) | LMNAHSD17B10HPGDHIF1APTGS1 | |
| Dobesilic Acid SCHEMBL214799 | 0.95 | LMNA (0.70) | LMNAHSD17B10HPGDHIF1APTGS1 | |
| Dobesilic Acid SCHEMBL78224 | 0.95 | LMNA (0.70) | LMNAHSD17B10HPGDHIF1APTGS1 | |
| Dobesilic Acid SCHEMBL15364076 | 0.95 | LMNA (0.70) | LMNAHSD17B10HPGDHIF1APTGS1 | |
| Dobesilic Acid SCHEMBL866670 | 0.95 | LMNA (0.70) | LMNAHSD17B10HPGDHIF1APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436045-B2 | Use of 2,5-dihydroxybenzene derivatives for treating actinic keratosis | AmDerma Pharmaceuticals, LLC (US) | 2013-05-07 | — | — | US | claimed |
| US-20120149938-A1 | Processes For The Preparation Of 2,5-Dihydroxybenzenesulfonic Acid Salts | AmDerma Pharmaceuticals, LLC (US) | 2012-06-14 | — | — | US | claimed |
| US-20110144337-A1 | PROCESSES FOR THE PREPARATION OF 2,5-DIHYDROXYBENZENESULFONIC ACID SALTS | ACTION MEDICINES S.L. (ES) | 2011-06-16 | — | — | US | claimed |
| EP-2313366-A2 | PROCESSES FOR THE PREPARATION OF 2,5-DIHYDROXYBENZENESULFONIC ACID SALTS | Action Medicines, S.L. (ES) | 2011-04-27 | — | — | EP | claimed |
| WO-2009083940-A2 | PROCESSES FOR THE PREPARATION OF 2,5-DIHYDROXYBENZENESULFONIC ACID SALTS | ACTION MEDICINES S.L. (ES) | 2009-07-09 | — | — | WO | claimed |
| US-6913694-B2 | Selective membrane having a high fouling resistance | SAEHAN INDUSTRIES INCORPORATION (KR) | 2005-07-05 | — | — | US | claimed |
| US-20030121844-A1 | Selective membrane having a high fouling resistance | SAEHAN INDUSTRIES INCORPORATION (KR) | 2003-07-03 | — | — | US | claimed |
| CN-117233312-A | Detection method of related substances in hydroquinone cream and application thereof | 广东人人康药业有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-112023726-B | Low-energy-consumption high-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-112023726-A | Low-energy-consumption high-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-12-04 | — | — | CN | disclosed |
| US-10632085-B2 | Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts | AmDerma Pharmaceuticals, LLC (US) | 2020-04-28 | — | — | US | disclosed |
| US-10632085-B2 | Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts | AmDerma Pharmaceuticals, LLC (US) | 2020-04-28 | — | — | US | disclosed |
| US-20180289645-A1 | Processes For The Preparation Of 2,5-Dihydroxybenzenesulfonic Acid Salts | ACTION MEDICINES, S.L. (ES) | 2018-10-11 | — | — | US | disclosed |
| US-20030121844-A1 | Selective membrane having a high fouling resistance | SAEHAN INDUSTRIES INCORPORATION (KR) | 2003-07-03 | — | — | US | disclosed |
| US-6100020-A | FORMING A SILVER HALIDE EMULSION, CHEMICAL OR OPTICAL SENSITIZATION, ADDING AN ARYL COMPOUND CONTAINING HYDROXY AND SULFONATE GROUPS, FINALLY COATING THE EMULSION | EASTMAN KODAK COMPANY (US) | 2000-08-08 | — | — | US | disclosed |
| EP-0903620-A1 | Process for the preparation of silver halide photographic element | Imation Corp. (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0903621-A1 | Process for the preparation of silver halide photographic element | Imation Corp. (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0524019-A1 | Hydraulic cement mixtures containing (dialkanol)aminoalkylphenols | W.R. Grace & Co.-Conn. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5102467-A | Adding a (dialkanol)aminomethyl phenol to enhance setting strength | W.R. GRACE & CO.-CONN. (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0009837-B1 | PHOTOGRAPHIC ELEMENT CONTAINING SUBSTITUTED 1-PHENYL-3-PYRAZOLIDINONE ELECTRON TRANSFER AGENT | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180289645-A1 | Processes For The Preparation Of 2,5-Dihydroxybenzenesulfonic Acid Salts | CYP24A1, CYP2S1, CYP21A2 | LMNA 2713/4885HSD17B10 440/4885HPGD 854/4885 |
| US-20110144337-A1 | PROCESSES FOR THE PREPARATION OF 2,5-DIHYDROXYBENZENESULFONIC ACID SALTS | KCNK5, CYP2S1, CYP26B1 | LMNA 2394/4885HSD17B10 279/4885HPGD 930/4885 |
| US-20120149938-A1 | Processes For The Preparation Of 2,5-Dihydroxybenzenesulfonic Acid Salts | KCNK5, CYP2S1, CYP26B1 | LMNA 2394/4885HSD17B10 279/4885HPGD 930/4885 |
| US-10632085-B2 | Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts | CYP24A1, CYP2S1, CYP21A2 | LMNA 2713/4885HSD17B10 440/4885HPGD 854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.