Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.65 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14502622 | 0.87 | KEAP1 (0.66) | KEAP1NFE2L2CNR1CNR2KMT2A | |
| SCHEMBL2705416 | 0.86 | CNR1 (0.55) | KEAP1NFE2L2SMN1; SMN2CNR1CNR2 | |
| SCHEMBL6518997 | 0.86 | KEAP1 (0.65) | KEAP1NFE2L2CNR1CNR2KMT2A | |
| SCHEMBL7821400 | 0.84 | LMNA (0.72) | KEAP1NFE2L2CNR1CNR2KMT2A | |
| SCHEMBL9721821 | 0.81 | CNR1 (0.56) | KEAP1NFE2L2SMN1; SMN2CNR1CNR2 | |
| SCHEMBL16894157 | 0.79 | KEAP1 (0.71) | KEAP1NFE2L2RORCKMT2ATSHR | |
| SCHEMBL2703770 | 0.78 | KEAP1 (0.54) | KEAP1NFE2L2CNR1CNR2RORC | |
| SCHEMBL7822866 | 0.77 | LMNA (0.61) | KEAP1NFE2L2KMT2AMAPK1PPARG | |
| SCHEMBL2006245 | 0.77 | ESR1 (0.60) | KEAP1NFE2L2KMT2ATSHRMAPK1 | |
| SCHEMBL13589964 | 0.77 | KEAP1 (0.55) | KEAP1NFE2L2SMN1; SMN2CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |