Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.53 |
| ▸ | CNR1 | P21554 | 8/20 | 0.53 |
| ▸ | ACHE | P22303 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12913014 | 0.86 | CNR2 (0.70) | CNR2CNR1ACHECYP1A2CYP2D6 | |
| SCHEMBL8043123 | 0.85 | CNR2 (0.74) | CNR2CNR1ACHECYP1A2CYP2D6 | |
| SCHEMBL7815982 | 0.81 | CNR2 (0.57) | CNR2CNR1ACHECYP1A2CYP2D6 | |
| SCHEMBL7818113 | 0.80 | CNR1 (0.56) | CNR2CNR1ACHECYP1A2CYP2D6 | |
| SCHEMBL12913013 | 0.74 | CNR2 (0.45) | CNR2CNR1ACHECYP1A2CYP2D6 | |
| SCHEMBL7808303 | 0.73 | CNR2 (0.51) | CNR2CNR1ACHECYP1A2CYP2D6 | |
| SCHEMBL12946210 | 0.72 | CNR2 (0.50) | CNR2CNR1ACHECYP1A2CYP2D6 | |
| SCHEMBL12913017 | 0.71 | CNR2 (0.42) | CNR2CNR1ACHECYP1A2CYP2D6 | |
| SCHEMBL27944549 | 0.71 | PTGER4 (0.49) | CNR2CNR1ACHECYP1A2CYP2D6 | |
| SCHEMBL7808408 | 0.71 | CNR2 (0.45) | CNR2CNR1ACHECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-A1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058503-A1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1999-11-18 | — | — | WO | disclosed |