Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.57 |
| ▸ | CNR1 | P21554 | 6/20 | 0.57 |
| ▸ | ACHE | P22303 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12913014 | 0.82 | CNR2 (0.70) | CNR2CNR1ACHESMN1; SMN2ALDH1A1 | |
| SCHEMBL7822340 | 0.81 | CNR2 (0.53) | CNR2CNR1ACHEMGLLABHD6 | |
| SCHEMBL7818113 | 0.75 | CNR1 (0.56) | CNR2CNR1ACHEKMT2ASMN1; SMN2 | |
| SCHEMBL7116425 | 0.73 | CNR2 (1.00) | CNR2CNR1ACHEBCHE | |
| SCHEMBL30060423 | 0.72 | CNR2 (0.52) | CNR2CNR1ACHECYP1A2HTR1A | |
| SCHEMBL6973326 | 0.72 | CNR2 (0.58) | CNR2CNR1ACHEKMT2ASMN1; SMN2 | |
| SCHEMBL27529329 | 0.72 | CNR2 (0.61) | CNR2CNR1ACHEKMT2ASMN1; SMN2 | |
| SCHEMBL7119866 | 0.72 | CNR2 (0.81) | CNR2CNR1ACHEKMT2AMEN1 | |
| SCHEMBL6964979 | 0.71 | CNR2 (0.60) | CNR2CNR1ACHESMN1; SMN2MGLL | |
| SCHEMBL8043123 | 0.71 | CNR2 (0.74) | CNR2CNR1ACHEKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-A1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058503-A1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1999-11-18 | — | — | WO | disclosed |