Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.45 |
| ▸ | CNR1 | P21554 | 7/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 5/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12913017 | 0.91 | CNR2 (0.42) | CNR2CNR1ACHEBCHECHRM2 | |
| SCHEMBL12913014 | 0.81 | CNR2 (0.70) | CNR2CNR1ACHECHRM2CHRM1 | |
| SCHEMBL7808408 | 0.77 | CNR2 (0.45) | CNR2CNR1ACHEBCHECHRM2 | |
| SCHEMBL7818113 | 0.76 | CNR1 (0.56) | CNR2CNR1ACHECHRM2CHRM1 | |
| SCHEMBL7808406 | 0.76 | MAPT (0.37) | CNR2CNR1ACHEBCHECHRM2 | |
| SCHEMBL7822340 | 0.74 | CNR2 (0.53) | CNR2CNR1ACHEBCHECHRM2 | |
| SCHEMBL19675194 | 0.72 | GLS (0.60) | CHRM2CHRM1KDM4EPOLBMAPT | |
| SCHEMBL16772015 | 0.70 | CASP3 (0.42) | KDM4EMAPTATM | |
| SCHEMBL12912991 | 0.70 | CYP3A4 (0.41) | ACHEBCHEBLM | |
| SCHEMBL7815982 | 0.70 | CNR2 (0.57) | CNR2CNR1ACHEBCHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868184-B2 | Multicore indazolinone library | The University of the University of St. Andrews (GB) | 2011-01-11 | — | — | US | disclosed |
| US-20070179294-A1 | Multicore indazolinone library | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179294-A1 | Multicore indazolinone library | IPMK, TTK, IWS1 | CNR2 4589/4885CNR1 4660/4885ACHE 1206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.