Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.77 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.77 |
| ▸ | MMP1 | P03956 | 4/20 | 0.70 |
| ▸ | MMP2 | P08253 | 4/20 | 0.70 |
| ▸ | MMP9 | P14780 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.65 |
| ▸ | PARP1 | P09874 | 2/20 | 0.63 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.63 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.63 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822564 | 1.00 | LPAR1 (0.77) | LPAR1LPAR2MMP1MMP2MMP9 | |
| SCHEMBL441805 | 0.88 | LPAR2 (1.00) | LPAR1LPAR2ALDH1A1CREBBPPARP1 | |
| SCHEMBL441804 | 0.88 | LPAR2 (1.00) | LPAR1LPAR2ALDH1A1CREBBPPARP1 | |
| SCHEMBL1552033 | 0.88 | LPAR2 (1.00) | LPAR1LPAR2ALDH1A1CREBBPPARP1 | |
| Iodide SCHEMBL1552156 | 0.86 | LPAR2 (0.96) | LPAR1LPAR2ALDH1A1CREBBPPARP1 | |
| Maleic Acid SCHEMBL27899766 | 0.85 | MMP1 (0.56) | LPAR1LPAR2MMP1MMP2MMP9 | |
| SCHEMBL21646072 | 0.83 | MMP1 (0.66) | LPAR1LPAR2MMP1MMP2MMP9 | |
| SCHEMBL21646071 | 0.83 | MMP1 (0.66) | LPAR1LPAR2MMP1MMP2MMP9 | |
| SCHEMBL11756411 | 0.83 | MMP1 (0.66) | LPAR1LPAR2MMP1MMP2MMP9 | |
| SCHEMBL705745 | 0.83 | MMP1 (1.00) | MMP1MMP2MMP9MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |