Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819153 | 0.80 | GRIN1 (0.41) | HTR7DRD2HTR2ADRD1HTR1A | |
| SCHEMBL7821213 | 0.75 | GRIN1 (0.50) | HTR7DRD2HTR2ADRD1HTR1A | |
| SCHEMBL7822657 | 0.71 | HTR7 (0.38) | HTR7DRD2HTR2ADRD1HTR1A | |
| SCHEMBL7977455 | 0.70 | HTR7 (0.40) | HTR7DRD2HTR2ADRD1HTR1A | |
| SCHEMBL7819195 | 0.70 | HTR7 (0.42) | HTR7DRD2HTR2AHTR1ADRD3 | |
| SCHEMBL7818373 | 0.67 | HTR7 (0.44) | HTR7DRD2HTR2ADRD1HTR1A | |
| SCHEMBL7816875 | 0.67 | HTR7 (0.38) | HTR7DRD2HTR2ADRD1HTR1A | |
| SCHEMBL7819559 | 0.67 | HTR7 (0.41) | HTR7DRD2HTR2ADRD1HTR1A | |
| SCHEMBL7808397 | 0.67 | HTR7 (0.39) | HTR7DRD2HTR2ADRD1HTR1A | |
| SCHEMBL7817762 | 0.66 | HTR7 (0.39) | HTR7DRD2HTR2ADRD1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749971-B1 | Thiopyran derivatives | SUNTORY LTD (JP) | 2001-03-14 | — | — | EP | disclosed |