Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16051336 | 0.87 | ALDH1A1 (0.67) | L3MBTL1TSHRRECQLPOLBMEN1 | |
| SCHEMBL30498780 | 0.86 | TSHR (0.97) | L3MBTL1TSHRRECQLPOLBMEN1 | |
| SCHEMBL22692601 | 0.86 | TSHR (0.97) | L3MBTL1TSHRRECQLPOLBMEN1 | |
| SCHEMBL4827189 | 0.85 | ALDH1A1 (0.69) | L3MBTL1TSHRRECQLPOLBMEN1 | |
| SCHEMBL22764320 | 0.83 | HTT (0.66) | L3MBTL1TSHRRECQLPOLBMEN1 | |
| SCHEMBL10720608 | 0.81 | TSHR (0.69) | L3MBTL1TSHRRECQLPOLBMEN1 | |
| SCHEMBL14882284 | 0.80 | TSHR (0.68) | L3MBTL1TSHRRECQLPOLBMEN1 | |
| SCHEMBL14882282 | 0.79 | TSHR (0.62) | TSHRRECQLPOLBMEN1KMT2A | |
| SCHEMBL2136069 | 0.78 | HPGD (0.71) | TSHRRECQLPOLBMEN1KMT2A | |
| SCHEMBL884737 | 0.78 | TSHR (0.60) | L3MBTL1TSHRRECQLPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |