Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820017 | 0.90 | CYP3A4 (0.65) | L3MBTL1POLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL15107476 | 0.90 | L3MBTL1 (0.74) | L3MBTL1ALDH1A1CYP3A4HPGDMEN1 | |
| SCHEMBL7109979 | 0.88 | POLB (0.65) | L3MBTL1POLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7111208 | 0.86 | ALDH1A1 (0.63) | L3MBTL1POLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL22529434 | 0.84 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL22529390 | 0.83 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL7098921 | 0.83 | CYP3A4 (0.69) | L3MBTL1ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL9079731 | 0.83 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1876366 | 0.83 | L3MBTL1 (0.69) | L3MBTL1ALDH1A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL7107371 | 0.82 | POLB (0.82) | L3MBTL1POLBALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |