Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927622 | 0.73 | GPR35 (0.50) | RXFP1ALDH1A1POLBKDM4EGRIA4 | |
| SCHEMBL4931290 | 0.72 | ALDH1A1 (0.41) | RXFP1ALDH1A1POLBGRIA4GPR35 | |
| SCHEMBL9365753 | 0.67 | RXFP1 (0.40) | RXFP1ALDH1A1POLBKDM4EGRIA4 | |
| SCHEMBL2808132 | 0.65 | GPR35 (0.52) | RXFP1ALDH1A1KDM4EGPR35NPSR1 | |
| SCHEMBL21192360 | 0.64 | GPR35 (0.40) | RXFP1ALDH1A1POLBKDM4EGPR35 | |
| SCHEMBL7243521 | 0.64 | GRIA4 (0.43) | RXFP1ALDH1A1POLBKDM4EGRIA4 | |
| Hydrochloric Acid SCHEMBL11597163 | 0.63 | GPR35 (0.50) | RXFP1ALDH1A1POLBKDM4EGPR35 | |
| SCHEMBL28361289 | 0.62 | GPR35 (0.48) | RXFP1ALDH1A1POLBKDM4EGPR35 | |
| SCHEMBL6968247 | 0.62 | GAA (0.43) | RXFP1ALDH1A1POLBKDM4EGRIA4 | |
| SCHEMBL10186093 | 0.61 | GPR35 (0.60) | RXFP1KDM4EGPR35NPSR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |