Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371745 | 0.82 | CA12 (0.46) | RAB9ACYP1A2CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL71884 | 0.80 | DGAT1 (0.68) | DGAT1RAB9APKMPOLBL3MBTL1 | |
| SCHEMBL1965917 | 0.80 | SMN1; SMN2 (0.51) | POLBL3MBTL1MAPTGAACYP1A2 | |
| SCHEMBL29723823 | 0.80 | DGAT1 (0.68) | DGAT1RAB9APKMPOLBL3MBTL1 | |
| SCHEMBL1970298 | 0.78 | KMT2A (0.44) | RAB9AMAPTGAACYP1A2CYP3A4 | |
| SCHEMBL9302975 | 0.77 | POLB (0.60) | DGAT1RAB9APKMPOLBL3MBTL1 | |
| SCHEMBL9302968 | 0.77 | POLB (0.60) | DGAT1RAB9APKMPOLBL3MBTL1 | |
| SCHEMBL609459 | 0.76 | TDP1 (0.41) | DGAT1RAB9APKMPOLBL3MBTL1 | |
| SCHEMBL30530049 | 0.76 | NAPRT (0.62) | DGAT1RAB9APKMPOLBL3MBTL1 | |
| SCHEMBL14519853 | 0.76 | NAPRT (0.62) | DGAT1RAB9APKMPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787726-B1 | NOVEL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTITUMOR AGENT | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-11-28 | — | — | EP | disclosed |