Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302975 | 1.00 | POLB (0.60) | POLBPKMDGAT1L3MBTL1RAB9A | |
| SCHEMBL9343294 | 0.84 | MAPK1 (0.50) | POLBPKML3MBTL1MAPTGAA | |
| SCHEMBL29723823 | 0.84 | DGAT1 (0.68) | POLBPKMDGAT1L3MBTL1RAB9A | |
| SCHEMBL71884 | 0.84 | DGAT1 (0.68) | POLBPKMDGAT1L3MBTL1RAB9A | |
| SCHEMBL3869968 | 0.81 | POLB (0.58) | POLBPKML3MBTL1RAB9AMAPT | |
| SCHEMBL9302681 | 0.79 | HRH3 (0.56) | RAB9AMAPTNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL5514528 | 0.78 | SMN1; SMN2 (0.54) | POLBPKML3MBTL1RAB9AMAPT | |
| SCHEMBL30876053 | 0.77 | PDCD1 (0.53) | RAB9AMAPTNPC1GAAKDM4E | |
| SCHEMBL7823348 | 0.77 | DGAT1 (0.59) | POLBPKMDGAT1L3MBTL1RAB9A | |
| SCHEMBL9448967 | 0.76 | CA12 (0.66) | RAB9AMAPTNPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356559-A | Optically active piperazinyl derivatives as liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |