Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | MMP14 | P50281 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | FPR2 | P25090 | 6/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | FPR1 | P21462 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173338 | 0.80 | CA1 (0.50) | MMP2CA12MAOAMAOBMEN1 | |
| SCHEMBL5511994 | 0.79 | CA12 (0.50) | CA12MEN1KMT2ACA9LMNA | |
| SCHEMBL3381061 | 0.79 | FPR2 (0.51) | MMP2MMP9MMP8MMP14CA12 | |
| SCHEMBL3972557 | 0.79 | FPR2 (0.51) | MMP2MMP9MMP8MMP14CA12 | |
| SCHEMBL5379371 | 0.78 | MAPT (0.50) | CA12MEN1KMT2ACA2CA9 | |
| SCHEMBL11184595 | 0.78 | NPC1 (0.47) | MMP2MMP9MMP8MMP14MEN1 | |
| SCHEMBL11178677 | 0.78 | CA12 (0.52) | MMP8CA12TGM2 | |
| SCHEMBL11411239 | 0.77 | MMP2 (0.51) | MMP2MMP9MMP8MMP14CA2 | |
| SCHEMBL11059129 | 0.76 | FPR2 (0.66) | MMP2MMP9MMP8MMP14CA12 | |
| SCHEMBL11205370 | 0.76 | FPR2 (0.66) | MMP2MMP9MMP8MMP14CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |