Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4548287 | 0.89 | MEN1 (0.61) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL5853268 | 0.86 | CXCR2 (0.74) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL11350134 | 0.83 | MEN1 (0.71) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL4548043 | 0.83 | SMN1; SMN2 (0.74) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL4920563 | 0.82 | MAPT (0.56) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL6799221 | 0.81 | RAB9A (0.73) | MAPTRAB9AHTTATMNPSR1 | |
| SCHEMBL4124525 | 0.81 | NTRK1 (0.55) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL3092811 | 0.79 | MAPT (0.51) | MAPTRAB9AMEN1KMT2ACXCR2 | |
| SCHEMBL10069535 | 0.78 | PTPN7 (0.73) | MAPTKMT2AALDH1A1CA12CA2 | |
| Deaminohydroxyvaline SCHEMBL7825097 | 0.78 | SMN1; SMN2 (0.48) | MAPTRAB9AHTTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |