Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261534 | 0.98 | PDE4B (0.60) | PDE4BHTTHSD11B1MEN1KMT2A | |
| SCHEMBL5055127 | 0.92 | HTT (0.68) | PDE4BHTTHSD11B1MEN1KMT2A | |
| SCHEMBL14930210 | 0.88 | PDE4B (0.62) | PDE4BHTTMEN1KMT2AMAPT | |
| SCHEMBL8569807 | 0.85 | KMT2A (0.53) | HTTHSD11B1MEN1KMT2AMAPT | |
| SCHEMBL7267945 | 0.85 | KMT2A (0.53) | HTTHSD11B1MEN1KMT2AMAPT | |
| SCHEMBL14261447 | 0.85 | GAA (0.54) | HTTHSD11B1MEN1KMT2AMAPT | |
| SCHEMBL10772675 | 0.85 | GAA (0.54) | HTTHSD11B1MEN1KMT2AMAPT | |
| SCHEMBL7898046 | 0.85 | GAA (0.54) | HTTHSD11B1MEN1KMT2AMAPT | |
| SCHEMBL15692727 | 0.84 | HSD11B1 (0.59) | HTTHSD11B1MEN1KMT2AMAPT | |
| SCHEMBL1038498 | 0.84 | HSD11B1 (0.59) | HTTHSD11B1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |