Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822412 | 0.90 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL7822408 | 0.90 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL7822120 | 0.84 | MEN1 (0.64) | ALDH1A1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL7822118 | 0.84 | MEN1 (0.64) | ALDH1A1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL7828680 | 0.81 | CYP3A4 (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7828683 | 0.81 | CYP3A4 (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7829189 | 0.80 | KMT2A (0.66) | ALDH1A1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL7829186 | 0.80 | KMT2A (0.66) | ALDH1A1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL7827937 | 0.80 | KMT2A (0.72) | ALDH1A1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL7827940 | 0.80 | KMT2A (0.72) | ALDH1A1MEN1KMT2ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |