Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829186 | 1.00 | KMT2A (0.66) | KMT2AL3MBTL1SMN1; SMN2MEN1PKM | |
| SCHEMBL7827940 | 0.95 | KMT2A (0.72) | KMT2AL3MBTL1SMN1; SMN2MEN1PKM | |
| SCHEMBL7827937 | 0.95 | KMT2A (0.72) | KMT2AL3MBTL1SMN1; SMN2MEN1PKM | |
| SCHEMBL27896475 | 0.89 | LMNA (0.66) | KMT2AL3MBTL1SMN1; SMN2MEN1PKM | |
| SCHEMBL7822412 | 0.89 | ALDH1A1 (0.65) | KMT2AL3MBTL1SMN1; SMN2MEN1PKM | |
| SCHEMBL7822408 | 0.89 | ALDH1A1 (0.65) | KMT2AL3MBTL1SMN1; SMN2MEN1PKM | |
| SCHEMBL27543049 | 0.84 | ALDH1A1 (0.70) | KMT2AL3MBTL1SMN1; SMN2MEN1PKM | |
| SCHEMBL22279488 | 0.83 | KMT2A (0.66) | KMT2AL3MBTL1SMN1; SMN2MEN1PKM | |
| SCHEMBL3057351 | 0.83 | LMNA (0.55) | KMT2AL3MBTL1SMN1; SMN2MEN1PKM | |
| SCHEMBL3057356 | 0.83 | LMNA (0.55) | KMT2AL3MBTL1SMN1; SMN2MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |