Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067835 | 0.85 | TDP1 (0.55) | HPSEPTPN1MEN1KMT2ATDP1 | |
| SCHEMBL15067191 | 0.85 | PTPN1 (0.54) | HPSEPTPN1MEN1KMT2ATDP1 | |
| SCHEMBL17374551 | 0.83 | PTPN1 (0.52) | HPSEPTPN1MEN1KMT2ATDP1 | |
| SCHEMBL7522323 | 0.81 | POLB (0.47) | PTPN1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7522329 | 0.81 | POLB (0.47) | PTPN1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL28883035 | 0.81 | SMN1; SMN2 (0.47) | TTRPOLBLMNASMN1; SMN2TSHR | |
| SCHEMBL15646828 | 0.81 | PGR (0.60) | PTPN1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL10416626 | 0.80 | HPSE (0.59) | HPSEPTPN1MEN1KMT2ATDP1 | |
| SCHEMBL7813399 | 0.78 | MEN1 (0.72) | HPSEMEN1KMT2ATDP1TTR | |
| SCHEMBL11244365 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2ATDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |