Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813399 | 0.82 | MEN1 (0.72) | HPSEMEN1KMT2ATTRALB | |
| SCHEMBL5700752 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2ATTRMAPTALDH1A1 | |
| SCHEMBL11849968 | 0.81 | HPSE (0.76) | HPSEMEN1KMT2ATTRTDP1 | |
| SCHEMBL8622495 | 0.81 | HPSE (0.80) | HPSEMEN1KMT2ATTRALB | |
| SCHEMBL10424095 | 0.81 | MEN1 (0.55) | HPSEMEN1KMT2ATTRALB | |
| SCHEMBL2020498 | 0.81 | PDE7A (0.73) | HPSEMEN1KMT2ATTRALB | |
| SCHEMBL10357075 | 0.81 | HPSE (0.56) | HPSEMEN1KMT2ATTRALB | |
| SCHEMBL31090813 | 0.81 | HPSE (0.56) | HPSEMEN1KMT2ATTRALB | |
| SCHEMBL1638040 | 0.81 | HSPB1 (0.66) | HPSEMEN1KMT2ATTRALB | |
| SCHEMBL1128860 | 0.81 | HPSE (0.56) | HPSEMEN1KMT2ATTRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221715-A | Substituted dibenz[b,f][1,4]oxazepin-11-yl pyridinium salts and derivatives thereof | AMERICAN CYANAMID COMPANY (US) | 1980-09-09 | — | — | US | claimed |
| WO-2021020481-A1 | METHOD FOR PRODUCING INTERMEDIATE OF IGURATIMOD DERIVATIVES, METHOD FOR PRODUCING IGURATIMOD, IGURATIMOD HAVING NOVEL CRYSTAL STRUCTURE, AND METHOD FOR PRODUCING SAME | 株式会社トクヤマ | 2021-02-04 | — | — | WO | disclosed |
| US-4954518-A | Antiinflammatory agents | TOYAMA CHEMICAL COMPANY, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0059884-B1 | BENZOFURANE DERIVATIVES, THEIR PREPARATION AND USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-05-22 | — | — | EP | disclosed |
| US-4411910-A | Benzofuran derivatives and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-10-25 | — | — | US | disclosed |
| EP-0059884-A1 | Benzofurane derivatives, their preparation and use | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-09-15 | — | — | EP | disclosed |