Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816824 | 0.93 | HTR1A (0.56) | HTR1AMAPTHTR2AKMT2AALDH1A1 | |
| SCHEMBL7824430 | 0.90 | HTR2A (0.57) | HTR1AMAPTHTR2AALDH1A1 | |
| SCHEMBL7825328 | 0.89 | HTR1A (0.66) | HTR1AHTR2A | |
| SCHEMBL7817700 | 0.87 | HTR2A (0.56) | HTR1AMAPTHTR2AALDH1A1 | |
| SCHEMBL7817427 | 0.87 | HTR1A (0.51) | HTR1AHTR2AALDH1A1MTNR1A | |
| SCHEMBL7817707 | 0.87 | MAPT (0.68) | HTR1AMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL7817397 | 0.86 | MAPT (0.58) | HTR1AMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL7817265 | 0.86 | HTR1A (0.53) | HTR1AMAPTHTR2AALDH1A1MTNR1A | |
| SCHEMBL7827977 | 0.86 | MAPT (0.57) | HTR1AMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL7838049 | 0.84 | MAPT (0.77) | MAPTKMT2AALDH1A1MEN1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861248-B1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PROD (US) | 2001-12-12 | — | — | EP | claimed |
| EP-0861248-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-09-02 | — | — | EP | claimed |
| US-5750724-A | SEROTONIN 5-HT REUPTAKE INHIBITORS; ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-12 | — | — | US | claimed |
| WO-1997017343-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-05-15 | — | — | WO | claimed |
| US-5750724-A | SEROTONIN 5-HT REUPTAKE INHIBITORS; ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |