Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 15/20 | 0.66 |
| ▸ | MPO | P05164 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816824 | 0.94 | HTR1A (0.56) | HTR1AHTR2ASLC6A4 | |
| SCHEMBL7823948 | 0.89 | HTR1A (0.54) | HTR1AHTR2A | |
| SCHEMBL7817427 | 0.88 | HTR1A (0.51) | HTR1AHTR2A | |
| SCHEMBL7824430 | 0.88 | HTR2A (0.57) | HTR1AHTR2A | |
| SCHEMBL7817265 | 0.87 | HTR1A (0.53) | HTR1AHTR2A | |
| SCHEMBL7817329 | 0.87 | HTR1A (0.64) | HTR1AMPOSLC6A4 | |
| SCHEMBL7831631 | 0.85 | MAPT (0.61) | HTR1AMPOSLC6A4 | |
| SCHEMBL7817700 | 0.85 | HTR2A (0.56) | HTR1AHTR2A | |
| SCHEMBL7826026 | 0.84 | HTR1A (0.47) | HTR1AHTR2A | |
| SCHEMBL7818119 | 0.84 | HTR1A (0.65) | HTR1AMPOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861248-B1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PROD (US) | 2001-12-12 | — | — | EP | claimed |
| EP-0861248-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-09-02 | — | — | EP | claimed |
| US-5750724-A | SEROTONIN 5-HT REUPTAKE INHIBITORS; ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-12 | — | — | US | claimed |
| WO-1997017343-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-05-15 | — | — | WO | claimed |
| US-5750724-A | SEROTONIN 5-HT REUPTAKE INHIBITORS; ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |