SCHEMBL7823966

SCHEMBL7823966

CCCCOC(=O)C1CC(=O)C(C(=O)OCCCC)CC1=O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
CHRM2 P08172 6/20 0.44
CHRM4 P08173 6/20 0.44
CHRM5 P08912 6/20 0.44
CHRM1 P11229 6/20 0.44
CHRM3 P20309 6/20 0.44
L3MBTL1 Q9Y468 3/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPK1 P28482 1/20 0.43
ATM Q13315 2/20 0.42
HPGD P15428 3/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8813353 0.93 CHRM2 (0.43) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL4683075 0.93 TSHR (0.47) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL4682822 0.93 TSHR (0.47) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL28830644 0.89 CHRM1 (0.42) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL7823958 0.83 KDM4E (0.33) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL3196831 0.80 ALDH1A1 (0.56) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL26679308 0.80 MAPK1 (0.40) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL5896955 0.80 MAPK1 (0.40) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL9511588 0.78 L3MBTL1 (0.39) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL10603303 0.78 NPC1 (0.48) ALDH1A1CHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110615743-A Lyotropic color-changing fluorescent compound and preparation method and application thereof 天津科技大学 2019-12-27 CN disclosed
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5659076-A Process for the production of 2,5-dianilino-terephthalic acids DSM CHEMIE LINZ GMBH (AT) 1997-08-19 US disclosed
US-5491255-A Process for the transesterification of dimethyl succinylsuccinate CHEMIE LINZ GMBH (AT) 1996-02-13 US disclosed
CN-1114431-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS (JP) 1996-01-03 CN disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed