Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6519705 | 0.83 | CYP2D6 (0.71) | CYP2D6KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL11888956 | 0.83 | CYP2D6 (0.71) | CYP2D6KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL6519630 | 0.81 | CYP2D6 (0.68) | CYP2D6KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL13353668 | 0.79 | CYP2D6 (0.66) | CYP2D6KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL735657 | 0.79 | POLB (0.80) | CYP2D6ALDH1A1TSHRPOLBCYP2C9 | |
| SCHEMBL7122592 | 0.79 | POLB (0.80) | CYP2D6ALDH1A1TSHRPOLBCYP2C9 | |
| SCHEMBL3830424 | 0.79 | POLB (0.80) | CYP2D6ALDH1A1TSHRPOLBCYP2C9 | |
| SCHEMBL7603412 | 0.79 | TSHR (0.68) | CYP2D6KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL2702763 | 0.79 | CYP2D6 (0.64) | CYP2D6KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL4821271 | 0.76 | CYP2D6 (0.61) | CYP2D6KMT2AALDH1A1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |