Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.80 |
| ▸ | PKM | P14618 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.67 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122592 | 1.00 | POLB (0.80) | POLBPKMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3830424 | 1.00 | POLB (0.80) | POLBPKMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7469413 | 0.91 | PKM (0.72) | POLBPKMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4526586 | 0.91 | POLB (0.69) | POLBPKMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6805741 | 0.91 | ALDH1A1 (0.81) | POLBPKMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1988224 | 0.91 | ALDH1A1 (0.81) | POLBPKMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14470279 | 0.91 | ALDH1A1 (0.75) | POLBPKMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20458879 | 0.89 | POLB (0.67) | POLBPKMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5365907 | 0.89 | POLB (0.67) | POLBPKMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20198535 | 0.89 | POLB (0.67) | POLBPKMALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985624-A2 | Single step method of radiofluorination of biologically active compounds or biomolecules | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-10-29 | — | — | EP | claimed |
| CN-119241533-A | Preparation method of tetrahydro-gamma-carboline | 湖北科技学院 | 2025-01-03 | — | — | CN | disclosed |
| CN-107075274-B | Polymers, methods and uses | 帝斯曼知识产权资产管理有限公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-109641900-A | Chelate compound | 通用电气医疗集团股份有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-108997215-A | A kind of preparation method of 1,2,3,4- tetrahydro isoquinoline derivative | 武汉大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-108864127-A | A kind of oxygen bridge double-heptene sulfamide compound and the preparation method and application thereof containing different alkyl chain lengths | 武汉大学 | 2018-11-23 | — | — | CN | disclosed |
| CN-107573335-A | A kind of hand oxazole alkyl compound and preparation method thereof | 安徽师范大学 | 2018-01-12 | — | — | CN | disclosed |
| US-9840478-B2 | Piperazine derivatives as HIV protease inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-12-12 | — | — | US | disclosed |
| EP-3209726-A1 | POLYMER, PROCESS AND USE | DSM IP Assets B.V. (NL) | 2017-08-30 | — | — | EP | disclosed |
| CN-107075274-A | Polymers, methods and uses | 帝斯曼知识产权资产管理有限公司 | 2017-08-18 | — | — | CN | disclosed |
| EP-0644182-B1 | Cyclohexane derivatives useful as potassium channel openers | EISAI CO LTD (JP) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997024390-A1 | LINEAR POLYMERS OF N-(2-1'-AZIRIDINO)ETHYL)FORMAMIDE, PROCESS FOR THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-07-10 | — | — | WO | disclosed |
| US-5605907-A | USEFUL AS A PREVENTIVE AND THERAPEUTIC AGENT FOR DISEASES AGAINST WHICH A POTASSIUM CHANNEL OPENING ACTION IS EFFICACIOUS | EISAI CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| US-5478839-A | Potassium channel modulator, bronchodilator agent, muscle relaxants, vasodilator | EISAI CO., LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0644182-A1 | Cyclohexane derivatives useful as potassium channel openers | Eisai Co., Ltd. (JP) | 1995-03-22 | — | — | EP | disclosed |
| CN-1023481-C | 2-Thiophenyloxyaetic acids, process for their preparation and pharmaceutical preparations containing them | CL PHARMA (AT) | 1994-01-12 | — | — | CN | disclosed |
| EP-0284892-B1 | THIENYLOXYACETIC ACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CL PHARMA AKTIENGESELLSCHAFT (AT) | 1990-10-31 | — | — | EP | disclosed |
| US-4877809-A | ANTITHROMBOTIC AGENTS | CL PHARMA AKTIENGESELLSCHAFT (AT) | 1989-10-31 | — | — | US | disclosed |
| CN-88101670-A | 2-thiophenyloxyacetic acid derivatives, process for their preparation and pharmaceutical preparations containing them | — | 1988-11-23 | — | — | CN | disclosed |
| EP-0284892-A1 | Thienyloxyacetic acid derivatives, a process for their preparation, and pharmaceutical compositions containing them | CL PHARMA AKTIENGESELLSCHAFT (AT) | 1988-10-05 | — | — | EP | disclosed |